What Drugs Contain Phenethylamine?
Phenethylamine is a naturally occurring compound that regulates mood, focus, and energy levels. Found in various foods, such as chocolate, it has gained attention due to its presence in specific drugs. Phenethylamine drugs contain this compound and are known for their stimulating effects, which can influence the central nervous system in both beneficial and harmful ways.
Some of these drugs include prescription medications for attention deficit hyperactivity disorder (ADHD), which can offer therapeutic benefits. However, several illicit stimulant drugs also contain phenethylamine, such as MDMA and methamphetamine. Furthermore, phenethylamine is sold as a dietary supplement, often promoted for boosting mood, aiding in weight loss, or enhancing energy levels.
While phenethylamine and its derivatives may provide short-term mood elevation or stimulating effects, they carry significant risks, particularly when misused. The consumption of drugs and supplements containing phenethylamine can result in serious physical and mental health issues, including addiction, overdose, and long-lasting psychological problems. Recognizing the potential dangers of these substances is crucial for making informed decisions and taking charge of one’s health and well-being. At WhiteSands, we help individuals overcome substance use disorders and reclaim their lives.
What Is Phenethylamine?
Phenethylamine (PEA) is a naturally occurring substance categorized as a trace amine, which means it exists in small quantities within the nervous system and shares structural similarities with neurotransmitters like dopamine, norepinephrine, and serotonin. This monoamine alkaloid acts as a stimulant, akin to other compounds such as amphetamines. PEA can be found in certain foods, including chocolate and protein-rich items, but it can also be synthesized in a laboratory setting.
PEA is involved in various biological processes, functioning as both a neuromodulator and neurotransmitter in the brain. Within the central nervous system, it can facilitate the release of specific neurotransmitters, including dopamine and serotonin, which are linked to mood, motivation, and overall well-being.
Due to its stimulating properties, PEA has been researched for its potential to enhance mood and is sometimes included in dietary supplements. As noted by WebMD, individuals may use phenethylamine to improve athletic performance, combat depression, manage obesity, and address other health issues, although substantial evidence supporting these applications is lacking.
It’s worth mentioning that the effects of PEA are typically short-lived, as it is quickly metabolized by enzymes like monoamine oxidase (MAO). Additionally, high doses of PEA or its use in supplement form may lead to adverse side effects, such as elevated blood pressure and heart rate, particularly in those who are sensitive to stimulants.
What Are the Common Drugs That Contain Phenethylamine?
Substances that originate from phenethylamine or possess a similar chemical structure are commonly known as phenethylamine drugs. The United Nations Office on Drugs and Crime classifies phenethylamines as a group of compounds with recognized psychoactive and stimulant properties, which includes amphetamine, methamphetamine, and MDMA.
Amphetamine is frequently prescribed for conditions like ADHD and narcolepsy and is chemically linked to phenethylamine. Methamphetamine, often referred to as crystal meth, is a potent stimulant that is usually manufactured illegally and carries a significant risk of addiction. MDMA, also known as ecstasy or molly, is another derivative of amphetamine associated with phenethylamine, commonly used in recreational settings.
In addition, there are various phenethylamine supplements promoted as fat burners, mood enhancers, or energy boosters, which may produce mild stimulant effects. Furthermore, the antidepressant Bupropion (Wellbutrin) shares a chemical structure similar to that of phenethylamine and can enhance its levels in the brain.
Is Phenethylamine a Controlled Substance?
Phenethylamine is a naturally occurring compound that is not classified as a controlled substance in the United States. However, its legal status can change based on its form and intended use. Generally, pure phenethylamine is not listed as a controlled substance, allowing for its legal purchase and possession. Supplements containing phenethylamine are frequently promoted as stimulants or mood enhancers in dietary products. It’s important to note that while the FDA does not regulate supplements as rigorously as pharmaceuticals, it does oversee their safety.
Conversely, many phenethylamine derivatives, particularly those resembling amphetamines—such as ADHD medications, methamphetamine, and MDMA—are classified as controlled substances. These derivatives often exhibit psychoactive properties and may be deemed illegal. This has increased scrutiny of phenethylamine-containing products, especially when advertised as having effects similar to those of controlled substances.
How Does Phenethylamine Affect the Body and Mind?
Phenethylamine (PEA) is a naturally occurring substance in the human body and found in trace amounts in certain foods, particularly dark chocolate, which is often linked to the pleasurable feelings associated with its consumption. Nevertheless, the levels of PEA in food are relatively low compared to the amounts that might produce noticeable effects. PEA is typically more concentrated in supplement form, resulting in more pronounced effects. However, because the body metabolizes it rapidly, these effects can diminish quickly, necessitating frequent dosing.
PEA impacts the body and mind in various ways, mainly by promoting the release of neurotransmitters such as dopamine, norepinephrine, and serotonin. Here’s a closer look at its effects:
- Mood Enhancement– Phenethylamine is often associated with feelings of euphoria and well-being, which can produce a “natural high” due to dopamine release.
- Mental Clarity – By enhancing dopamine and norepinephrine, PEA can improve focus, mental clarity, and alertness.
- Stimulant Effects – PEA is structurally similar to amphetamines and, as such, has mild stimulant-like effects.
- Appetite Suppression – Some people report a loss of appetite when using phenethylamine-containing supplements.
- Increased Heart Rate and Blood Pressure – Like other stimulants, phenethylamine may raise heart rate and blood pressure, which can be particularly concerning for people with heart conditions.
- Anxiety and Jitteriness – At higher doses, phenethylamine may induce anxiety-like symptoms, such as nervousness, restlessness, or jitteriness, due to its stimulating effects on the nervous system.
- Serotonin Imbalance – There are concerns that excessive intake of phenethylamine could disrupt serotonin levels, potentially leading to side effects like headaches, agitation, or, in rare instances, serotonin syndrome, a serious condition caused by elevated serotonin in the brain.
Although phenethylamine is less addictive than substances such as cocaine or amphetamines, some individuals might develop a psychological reliance on the euphoria or enhanced performance it can provide. Over time, users may build a tolerance to PEA, leading to a “crash” once its effects diminish, which can encourage further use. Research published in the journal Psychopharmacology indicates that dietary supplements containing PEA analogs could pose a significant risk for abuse when used recreationally.
In contrast, drugs like methamphetamine, MDMA, and certain designer substances have a much higher potential for drug addiction. These drugs produce effects similar to phenethylamine but are far more intense, increasing the risk of overdose. While PEA supplements are often labeled as “natural,” they can still have strong effects, especially when consumed in large doses or combined with other stimulants, heightening the chances of overdose or serious health issues.
Contact WhiteSands Treatment to Learn More About Phenethylamine Drugs and Addiction Treatment
It is essential to be cautious about using phenethylamine drugs and supplements, especially when mixed with other stimulants or taken in excess. When individuals become dependent on these substances, they often struggle to break free from the cycle of abuse despite the devastating consequences. Fortunately, WhiteSands Treatment offers addiction recovery programs in Florida that assist individuals in overcoming substance abuse related to phenethylamine and guide them toward sustainable recovery and improved mental health. Our caring team is committed to delivering personalized care that meets your specific needs, utilizing evidence-based therapies and support throughout your recovery journey.
If you or someone you know is struggling with substance abuse, don’t wait any longer to seek help. Contact WhiteSands Treatment today at 877-855-3470 to learn more about the risks linked to phenethylamine drugs or to connect with one of our counselors and start your path to recovery with us.
External Sources
- WebMD – Phenethylamine (PEA) – Uses, Side Effects, and More
- United Nations Office on Drugs and Crime – Details for Phenethylamines
- Psychopharmacology – Reinforcing effects of phenethylamine analogs found in dietary supplements
If you or a loved one needs help with abuse and/or treatment, please call the WhiteSands Treatment at (877) 855-3470. Our addiction specialists can assess your recovery needs and help you get the addiction treatment that provides the best chance for your long-term recovery.
About the Author
Jackie has been involved in the substance abuse and addiction treatment sector for over five years and this is something that she is truly eager about. She has a passion for writing and continuously works to create informative pieces that not only educate and inform the public about the disease of addiction but also provide solutions for those who struggle with drug and alcohol abuse.
