Can You Drink on Wellbutrin?

Drinking alcohol while taking Wellbutrin (bupropion) is generally not recommended due to significant health risks. Mixing Wellbutrin and alcohol can increase the risk of seizures and intensify other adverse effects like dizziness, confusion, anxiety, and impaired judgment. Furthermore, alcohol is a central nervous system (CNS) depressant that can counteract the antidepressant effects of Wellbutrin, potentially worsening symptoms of depression. If you are planning to drink alcohol while on Wellbutrin, it is crucial to consult with your healthcare provider first, as they can advise you on the risks and potential consequences of mixing these substances.

alcohol and wellbutrin

Table of contents

» What Is Wellbutrin?

» Why Do Doctors Advise Against Mixing Wellbutrin and Alcohol?

» Does Drinking Alcohol Increase the Risk of Seizures on Wellbutrin?

» Should You Tell Your Doctor If You Plan to Drink While on Wellbutrin?

» Key Takeaways on Wellbutrin and Alcohol

» Resources


What Is Wellbutrin?

Wellbutrin, which is generically known as bupropion, is a prescribed medication aimed at treating depression, seasonal affective disorder (SAD), and aiding in smoking cessation, as noted by MedlinePlus. Occasionally, Wellbutrin is also utilized “off-label” for various other conditions, including depression linked to bipolar disorder, ADHD, and sexual dysfunction induced by antidepressants.

It is categorized as an atypical antidepressant, indicating that it operates differently from many standard antidepressants, like selective serotonin reuptake inhibitors (SSRIs), and is less prone to causing sexual side effects and weight gain compared to SSRIs.

This medication works by affecting the levels of certain chemicals in the brain, primarily dopamine and norepinephrine, to prolong the duration of these neurotransmitters. These chemicals play a crucial role in regulating mood, motivation, and other functions; thus, by elevating their levels, Wellbutrin aids in alleviating depressive symptoms and enhancing overall well-being. While Wellbutrin starts affecting neurotransmitter levels within hours, its full therapeutic effects may not be felt for weeks.

Like any medication, Wellbutrin can lead to a variety of side effects. Mild side effects are the most common and may lessen over time as the body adjusts, which include:

  • Insomnia
  • Dry mouth
  • Headache
  • Nausea, vomiting, or stomach pain
  • Constipation
  • Dizziness
  • Increased sweating
  • Anxiety, agitation, or restlessness
  • Loss of appetite or weight loss
  • Rapid heartbeat

Serious side effects are less common but may require immediate attention. Seizures are one of the most serious risks associated with Wellbutrin, which increases with higher doses or if there are pre-existing conditions. Wellbutrin may also cause an increase in blood pressure, suicidal thoughts or behavior, and manic episodes.


Why Do Doctors Advise Against Mixing Wellbutrin and Alcohol?

Doctors strongly caution against mixing Wellbutrin and alcohol due to serious and potentially life-threatening risks. This combination not only intensifies side effects but also undermines the effectiveness of the medication and increases the risk of dangerous behaviors or medical emergencies.

  • Increased Risk of Side Effects: Both Wellbutrin and alcohol can lead to dizziness, drowsiness, impaired judgment, nausea, and confusion. These effects become more pronounced when used together, creating dangerous scenarios such as accidents or falls.
  • Reduced Alcohol Tolerance: Wellbutrin may lower your tolerance to alcohol, meaning that even a small quantity can result in significant intoxication and increased impairment. Coupled with intensified side effects like drowsiness, this raises the risk of excessive alcohol consumption, which could lead to alcohol poisoning—a serious and potentially fatal condition. Alcohol poisoning can result in choking on vomit, respiratory depression, hypothermia, severe dehydration, brain damage, coma, or even death.
  • Worsening Mental Health Symptoms: As a central nervous system (CNS) depressant, alcohol can negate the antidepressant benefits of Wellbutrin. Although alcohol may initially induce feelings of relaxation, reduced anxiety, or a temporary uplift in mood, these effects are short-lived. They can ultimately worsen mental health by disrupting norepinephrine and dopamine regulation.
  • Risk of Alcohol Dependence: Many people suffering from depression or anxiety turn to alcohol for relief, which can create a harmful cycle where alcohol temporarily alleviates symptoms but ultimately exacerbates them, leading to increased consumption. Such patterns can result in alcohol dependence and addiction, along with deteriorating mental health issues.

Does Drinking Alcohol Increase the Risk of Seizures on Wellbutrin?

Seizures are uncommon yet serious side effects associated with Wellbutrin. Consuming alcohol greatly heightens the risk of seizures, which is one of the primary reasons doctors strongly recommend against mixing the two. Both Wellbutrin and alcohol lower the seizure threshold, making the brain more vulnerable to abnormal electrical activity that can trigger a seizure. When these substances are combined, the seizure-inducing effects are intensified, resulting in a greater chance of experiencing a seizure than if one were to take Wellbutrin or drink alcohol separately.

People who frequently consume large amounts of alcohol or suffer from an alcohol use disorder and suddenly stop drinking may face alcohol withdrawal syndrome, a potentially life-threatening condition due to the risk of seizures. Healthline highlights that undergoing alcohol withdrawal while on Wellbutrin further elevates the risk of seizures, along with other severe side effects, which include:

  • Severe shaking and tremors
  • Nausea and vomiting
  • Confusion and disorientation
  • Hallucinations and paranoia

It is crucial for anyone at risk of alcohol withdrawal while taking Wellbutrin to do so under medical supervision at a drug and alcohol detox center in Florida. A medical detox program can offer continuous monitoring, along with anticonvulsants and other medications to ensure safety during the alcohol withdrawal process.


Talk to Our Recovery Specialist
Transform Your Life Today
Talk to Our Recovery Specialist

Call Now: (239) 237-5473


What our customers are saying


Should You Tell Your Doctor If You Plan to Drink While on Wellbutrin?

While some individuals may manage to drink occasionally or socially while taking antidepressants like Wellbutrin, it is always advisable to consult your doctor. They can evaluate your specific risks, modify your treatment plan, and suggest safer alternatives. However, due to the intricate interactions and the potential for exacerbating mental health issues, your doctor will likely recommend completely avoiding alcohol consumption.

To reduce the chances of experiencing a seizure or other serious side effects while on Wellbutrin, it’s essential to be transparent with your doctor regarding your drinking habits. This includes how much you consume at once, the frequency of your drinking, and the duration of your current drinking pattern. By openly discussing your alcohol intake, your doctor can better determine if you have an alcohol use disorder or are at risk of developing one. They can then provide suitable support, resources, and referrals to specialists for alcohol addiction treatment in Florida.


Talk to Our Recovery Specialist
Transform Your Life Today
Talk to Our Recovery Specialist

Call Now: (239) 237-5473


wellbutrin mixed with alcohol

Key Takeaways on Wellbutrin and Alcohol

  • Mixing Alcohol with Wellbutrin is Dangerous: Combining Wellbutrin and alcohol is generally discouraged due to serious health risks, including seizures and worsening side effects.
  • Wellbutrin Can Decrease Alcohol Tolerance: Even consuming minimal amounts of alcohol while taking Wellbutrin can result in extreme intoxication and potentially lead to alcohol poisoning, which can be life-threatening.
  • Increased Seizure Risks: Both alcohol and Wellbutrin reduce the seizure threshold, meaning that individuals are at a heightened risk of experiencing a seizure when using both substances together.
  • Alcohol May Interfere with Wellbutrin Treatment: Being a CNS depressant, alcohol can negate the beneficial effects of Wellbutrin, potentially exacerbating symptoms of depression and anxiety.
  • Greater Risks of Alcohol Withdrawal: Individuals with alcohol use disorder who abruptly cease drinking while on Wellbutrin face a higher likelihood of experiencing severe alcohol withdrawal symptoms, including seizures, confusion, and hallucinations.
  • Always Consult Your Healthcare Provider: If you intend to consume alcohol while taking Wellbutrin, it is crucial to discuss this with your healthcare provider. They can evaluate your risk, modify your treatment plan, and assess your drinking patterns for potential alcohol use disorder.

If you or a loved one is facing challenges with alcohol use while on Wellbutrin, it is crucial to seek professional help. At WhiteSands Treatment in Florida, we understand the complex risks associated with combining Wellbutrin and alcohol, which include a heightened risk of seizures not only during active drinking but also during withdrawal from alcohol.

Our medical detox programs offer 24/7 support and medications to ensure safety when stopping drinking while on Wellbutrin, in addition to providing dual diagnosis treatment to tackle underlying mental health concerns. We specialize in helping individuals navigate the challenges of co-occurring disorders with tailored treatment plans and evidence-based therapies, including medication management.

Reach out to WhiteSands Alcohol and Drug Rehab today at 877-855-3470 to discover more about our recovery programs or to begin the admissions process.


Resources

If you or a loved one needs help with abuse and/or treatment, please call the WhiteSands Treatment at (877) 855-3470. Our addiction specialists can assess your recovery needs and help you get the addiction treatment that provides the best chance for your long-term recovery.

About the Author

Jaclyn

Jackie has been involved in the substance abuse and addiction treatment sector for over five years and this is something that she is truly eager about. She has a passion for writing and continuously works to create informative pieces that not only educate and inform the public about the disease of addiction but also provide solutions for those who struggle with drug and alcohol abuse.