Symtan is marketed as a decongestant, antihistamine and cough suppressant. It is the brand name for the generic combination of bromphenramine, hydrocodone and pseudoephedrine. Bromphenramine is the anti-histamine component of Symtan that reduces naturally occurring histamines in the body that can cause inflammation and a host of other adverse conditions. Antihistamines help to reduce sneezing and watery eyes.

Hydrocodone is a semi-synthetic opioid or narcotic that is derived from the opium poppy plant. It contributes the analgesic and cough suppressant ingredient that works by depressing the cough reflex which minimize dry coughing.

Pseudoephedrine is classified as suspension salts and are usually found in most over the counter decongestant medications. These salts are derived from the alkaloids of various plants or obtained through a yeast fermentation process. Pseudoephedrine works as a decongestant to shrink dilated blood vessels in the nasal passages that cause congestion and a stuffy nose.

Symtan is available by prescription only in a liquid formulation. This drug is listed as a stimulant by the World Anti-doping Agency (WADA). Stimulants increase cardiovascular activity, reduce fatigue and can cause mood modifications. They are in essence, psychoactive drugs that temporarily enhance physical and mental abilities. For the purposes of this product, stimulants help to counter fatigue, reduce headaches as well as offset the narcotic effects of hydrocodone.

Drug Classification

The Food and Drug Administration (FDA) has classified Symtan A as a Schedule II controlled substance. This designation indicate that this product has current accepted medical use with a high potential for abuse and the possibility of severe psychological or physical dependence. The Drug Enforcement Administration (DEA) reclassified all hydrocodone combination products such as Symtan from Schedule III to Schedule II Controlled Substances. Drugs under this classification are subject to regulatory controls and criminal sanctions enforceable by the DEA regarding importation, manufacture, distribution, research and possession.

Use and Abuse of Symtan

The primary use for this medication is to alleviate upper respiratory infections such as allergies, sinus misery, as well as cold and flu symptoms. However, due to the presence of hydrocodone in this product, euphoria is a potential side effect that may cause some users to form a psychological dependency on the drug. This high potential for Symtan abuse occurs primarily because hydrocodone is a highly addictive substance that in some studies is shown to impact some users faster than others. Common side effects from the prescribed use of Symtan may include:

  • Diarrhea or Constipation
  • Dizziness
  • Drowsiness
  • Headache
  • Excitable, jittery or nervous
  • Loss of appetite
  • Stomach ache

Abuse of Symtan that entails habitual consumption of high doses of the drug over a period of more than two three weeks can result in withdrawal symptoms when the drug is withheld. These withdrawal symptoms can vary in severity and last for an indefinite period of time. Withdrawal symptoms can also escalate rapidly and pose a health risk if left unchecked. Seek medical attention if cessation of Symtan triggers withdrawal symptoms such as:

  • Perspiration and chills,
  • Nausea and vomiting
  • Swelling of the face, tongue or throat
  • Trouble breathing


There are instances where drug interaction or use of other substances such as alcohol or illicit drugs can cause a drug overdose when using Symtan. Drug interactions also increase the risk of a fatality. Symptoms of an overdose may include but is not limited to:

  • Mental confusion
  • Cold and clammy skin
  • Rapid heart beat
  • Fainting away
  • Respiratory depression or trouble breathing
  • Seizures
  • Coma


Treatment for Symtan abuse varies based on duration of use, physical and mental health of the individual and the drug combinations if any that are being abused. Treatment options can include detoxification followed by a comprehensive program to address the issues presented by addiction. At our Drug Rehab Treatment Centers, we take an integrative approach that utilize evidence-based remedies drawn from conventional, holistic and cutting edge protocols. Our board certified doctors and nurses have firsthand experience with addiction and are able to provide the empathy and expertise to get you through the rehabilitation process.

If you or a loved one is experiencing a dependency on Symtan, call our Drug Rehab Treatment Centers today at 877-855-3470. We can help.